View source for 4n68


==Crystal structure of an internal FN3 domain from human Contactin-5 [PSI-NYSGRC-005804]==
<StructureSection load='4n68' size='340' side='right'caption='[[4n68]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4n68]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N68 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4N68 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4n68 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n68 OCA], [https://pdbe.org/4n68 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4n68 RCSB], [https://www.ebi.ac.uk/pdbsum/4n68 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4n68 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CNTN5_HUMAN CNTN5_HUMAN] Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity in the cerebral cortical neurons but not in hippocampal neurons. Probably involved in neuronal activity in the auditory system (By similarity).
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Almo SC]]
[[Category: Attonito J]]
[[Category: Banu R]]
[[Category: Bhosle R]]
[[Category: Calarese DA]]
[[Category: Casadevall A]]
[[Category: Celikgil A]]
[[Category: Chamala S]]
[[Category: Chan MK]]
[[Category: Chowdhury S]]
[[Category: Fiser A]]
[[Category: Garforth SJ]]
[[Category: Glenn AS]]
[[Category: Hillerich B]]
[[Category: Khafizov K]]
[[Category: Kumar PR]]
[[Category: Love JD]]
[[Category: Patel H]]
[[Category: Patel R]]
[[Category: Seidel RD]]
[[Category: Smith B]]
[[Category: Stead M]]
[[Category: Toro R]]