View source for 4nae


==PcrB from Geobacillus kaustophilus, with bound G1P==
<StructureSection load='4nae' size='340' side='right'caption='[[4nae]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4nae]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_kaustophilus_HTA426 Geobacillus kaustophilus HTA426]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NAE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NAE FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1GP:SN-GLYCEROL-1-PHOSPHATE'>1GP</scene>, <scene name='pdbligand=PE4:2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL'>PE4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nae FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nae OCA], [https://pdbe.org/4nae PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nae RCSB], [https://www.ebi.ac.uk/pdbsum/4nae PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nae ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PCRB_GEOKA PCRB_GEOKA] Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales. To a much lesser extent, is also able to use geranylgeranyl diphosphate (GGPP; C20) as the prenyl donor.<ref>PMID:21761520</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Geobacillus kaustophilus HTA426]]
[[Category: Large Structures]]
[[Category: Babinger P]]
[[Category: Beer B]]
[[Category: Guldan H]]
[[Category: Kapetaniou E]]
[[Category: Kumpula EP]]
[[Category: Peterhoff D]]
[[Category: Rajendran C]]
[[Category: Sterner R]]
[[Category: Wierenga RK]]