View source for 4ndz


==Structure of Maltose Binding Protein fusion to 2-O-Sulfotransferase with bound heptasaccharide and PAP==
<StructureSection load='4ndz' size='340' side='right'caption='[[4ndz]], [[Resolution|resolution]] 3.45&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4ndz]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_UMEA_3304-1 Escherichia coli UMEA 3304-1] and [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NDZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NDZ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.45&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A3P:ADENOSINE-3-5-DIPHOSPHATE'>A3P</scene>, <scene name='pdbligand=BDP:BETA-D-GLUCOPYRANURONIC+ACID'>BDP</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=GNS:N-SULFO-ALPHA-D-GLUCOSAMINE'>GNS</scene>, <scene name='pdbligand=IDR:L-IDURONIC+ACID'>IDR</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene>, <scene name='pdbligand=NPO:P-NITROPHENOL'>NPO</scene>, <scene name='pdbligand=PRD_900001:alpha-maltose'>PRD_900001</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ndz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ndz OCA], [https://pdbe.org/4ndz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ndz RCSB], [https://www.ebi.ac.uk/pdbsum/4ndz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ndz ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MALE_ECOLI MALE_ECOLI] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides.[https://www.uniprot.org/uniprot/HS2ST_CHICK HS2ST_CHICK] Catalyzes the transfer of sulfate to the C2-position of selected hexuronic acid residues within the maturing heparan sulfate (HS). 2-O-sulfation within HS, particularly of iduronate residues, is essential for HS to participate in a variety of high-affinity ligand-binding interactions and signaling processes.<ref>PMID:19022906</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli UMEA 3304-1]]
[[Category: Gallus gallus]]
[[Category: Large Structures]]
[[Category: Hsieh P]]
[[Category: Krahn JM]]
[[Category: Liu C]]
[[Category: Liu J]]
[[Category: Pedersen LC]]
[[Category: Perera L]]
[[Category: Sheng J]]
[[Category: Xu Y]]