View source for 4nec


==Conversion of a Disulfide Bond into a Thioacetal Group during Echinomycin Biosynthesis==
<StructureSection load='4nec' size='340' side='right'caption='[[4nec]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4nec]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_echinatus Streptomyces echinatus] and [https://en.wikipedia.org/wiki/Streptomyces_lasalocidi Streptomyces lasalocidi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NEC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NEC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=15P:POLYETHYLENE+GLYCOL+(N=34)'>15P</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DSN:D-SERINE'>DSN</scene>, <scene name='pdbligand=MVA:N-METHYLVALINE'>MVA</scene>, <scene name='pdbligand=N2C:N,S-DIMETHYLCYSTEINE'>N2C</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NCY:N-METHYLCYSTEINE'>NCY</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=QUI:2-CARBOXYQUINOXALINE'>QUI</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nec OCA], [https://pdbe.org/4nec PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nec RCSB], [https://www.ebi.ac.uk/pdbsum/4nec PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nec ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q0X0A7_STRLS Q0X0A7_STRLS] 
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Streptomyces echinatus]]
[[Category: Streptomyces lasalocidi]]
[[Category: Bibby J]]
[[Category: Fang M]]
[[Category: Hotta K]]
[[Category: Keegan RM]]
[[Category: Kim C-Y]]
[[Category: Lian M]]
[[Category: Ranganathan S]]
[[Category: Rigden DJ]]
[[Category: Sato M]]
[[Category: Watanabe K]]
[[Category: Winn MD]]