View source for 4nei


==Alg17c PL17 Family Alginate Lyase==
<StructureSection load='4nei' size='340' side='right'caption='[[4nei]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4nei]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharophagus_degradans_2-40 Saccharophagus degradans 2-40]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NEI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NEI FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nei FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nei OCA], [https://pdbe.org/4nei PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nei RCSB], [https://www.ebi.ac.uk/pdbsum/4nei PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nei ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/EALGL_SACD2 EALGL_SACD2] Catalyzes the depolymerization of alginate through an exolytic mode of action, via a beta-elimination mechanism. Preferentially acts on oligoalginates with degrees of polymerization higher than 2 to produce the alginate monomer, 4-deoxy-L-erythro-5-hexoseulose uronic acid.<ref>PMID:22281843</ref> <ref>PMID:24478312</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharophagus degradans 2-40]]
[[Category: Nair SK]]
[[Category: Park DS]]