View source for 4nlh


==SKICH domain of human TAX1BP1==
<StructureSection load='4nlh' size='340' side='right'caption='[[4nlh]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4nlh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NLH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NLH FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nlh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nlh OCA], [https://pdbe.org/4nlh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nlh RCSB], [https://www.ebi.ac.uk/pdbsum/4nlh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nlh ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TAXB1_HUMAN TAXB1_HUMAN] Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade.<ref>PMID:10435631</ref> <ref>PMID:10920205</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Du Z]]
[[Category: Huang X]]
[[Category: Wang G]]
[[Category: Yang Y]]
[[Category: Zhu J]]