View source for 4ogl


==X-ray structure uridine phosphorylase from Vibrio cholerae in complex with thymine at 1.25 A resolution==
<StructureSection load='4ogl' size='340' side='right'caption='[[4ogl]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4ogl]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae_O1_biovar_El_Tor_str._N16961 Vibrio cholerae O1 biovar El Tor str. N16961]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OGL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OGL FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.249&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=TDR:THYMINE'>TDR</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ogl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ogl OCA], [https://pdbe.org/4ogl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ogl RCSB], [https://www.ebi.ac.uk/pdbsum/4ogl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ogl ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q9KT71_VIBCH Q9KT71_VIBCH] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.[RuleBase:RU361131]

==See Also==
*[[Uridine phosphorylase 3D structures|Uridine phosphorylase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Vibrio cholerae O1 biovar El Tor str. N16961]]
[[Category: Betzel C]]
[[Category: Gabdoulkhakov AG]]
[[Category: Lashkov AA]]
[[Category: Mikhailov AM]]
[[Category: Prokofev II]]