View source for 4orf


==cAMP-binding acyltransferase from Mycobacterium smegmatis, mutant R95K==
<StructureSection load='4orf' size='340' side='right'caption='[[4orf]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4orf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_smegmatis_MC2_155 Mycolicibacterium smegmatis MC2 155]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ORF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ORF FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4orf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4orf OCA], [https://pdbe.org/4orf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4orf RCSB], [https://www.ebi.ac.uk/pdbsum/4orf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4orf ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PAT_MYCS2 PAT_MYCS2] Catalyzes specifically the acetylation of the epsilon-amino group of a highly conserved lysine residue in acetyl-CoA synthetase (ACS) and of the universal stress protein (USP) MSMEG_4207. Acetylation results in the inactivation of ACS activity and could be important for mycobacteria to adjust to environmental changes.<ref>PMID:20507997</ref> <ref>PMID:21627103</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycolicibacterium smegmatis MC2 155]]
[[Category: Podobnik M]]
[[Category: Rebolj K]]
[[Category: Visweswariah SS]]