View source for 4pwy


==Crystal structure of a Calmodulin-lysine N-methyltransferase fragment==
<StructureSection load='4pwy' size='340' side='right'caption='[[4pwy]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4pwy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PWY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PWY FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pwy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pwy OCA], [https://pdbe.org/4pwy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pwy RCSB], [https://www.ebi.ac.uk/pdbsum/4pwy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pwy ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/CMKMT_HUMAN CMKMT_HUMAN] Atypical hypotonia - cystinuria syndrome;2p21 microdeletion syndrome without cystinuria;2p21 microdeletion syndrome. 
== Function ==
[https://www.uniprot.org/uniprot/CMKMT_HUMAN CMKMT_HUMAN] Catalyzes the trimethylation of 'Lys-116' in calmodulin.<ref>PMID:20975703</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Arrowsmith CH]]
[[Category: Bountra C]]
[[Category: Brown PJ]]
[[Category: Edwards AM]]
[[Category: Hong BS]]
[[Category: Li Y]]
[[Category: Tempel W]]
[[Category: Walker JR]]