View source for 4q77


==Crystal structure of Rot, a global regulator of virulence genes in Staphylococcus aureus==
<StructureSection load='4q77' size='340' side='right'caption='[[4q77]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4q77]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_MRSA252 Staphylococcus aureus subsp. aureus MRSA252]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q77 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Q77 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.77&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4q77 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q77 OCA], [https://pdbe.org/4q77 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4q77 RCSB], [https://www.ebi.ac.uk/pdbsum/4q77 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4q77 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ROT_STAAR ROT_STAAR] Global regulator with both positive and negative effects that mediates modulation of several genes involved in virulence. Also, modulates the expression of genes not previously implicated in pathogenesis (By similarity).
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</StructureSection>
[[Category: Large Structures]]
[[Category: Staphylococcus aureus subsp. aureus MRSA252]]
[[Category: Fan X]]
[[Category: Li X]]
[[Category: Teng M]]
[[Category: Zhu Y]]