View source for 4qgm


==Acireductone dioxygenase from Bacillus anthracis with cadmium ion in active center==
<StructureSection load='4qgm' size='340' side='right'caption='[[4qgm]], [[Resolution|resolution]] 2.97&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4qgm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis_str._'Ames_Ancestor' Bacillus anthracis str. 'Ames Ancestor']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QGM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QGM FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.97&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qgm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qgm OCA], [https://pdbe.org/4qgm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qgm RCSB], [https://www.ebi.ac.uk/pdbsum/4qgm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qgm ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MTND_BACAN MTND_BACAN] Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity).

==See Also==
*[[Dioxygenase 3D structures|Dioxygenase 3D structures]]
__TOC__
</StructureSection>
[[Category: Bacillus anthracis str. 'Ames Ancestor']]
[[Category: Large Structures]]
[[Category: Anderson WF]]
[[Category: Borowski T]]
[[Category: Chruszcz M]]
[[Category: Cooper DR]]
[[Category: Milaczewska AM]]
[[Category: Minor W]]
[[Category: Shabalin IG]]