View source for 4qhc


==Structure of M.Tuberculosis Betalactamase (Blac) with inhibitor having novel mechanism==
<StructureSection load='4qhc' size='340' side='right'caption='[[4qhc]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4qhc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QHC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QHC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.899&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=33V:(3R,6R,7S)-7-[(2R,3AR)-HEXAHYDROPYRAZOLO[1,5-C][1,3]THIAZIN-2-YL]-6-(HYDROXYMETHYL)-1,4-THIAZEPANE-3-CARBOXYLIC+ACID'>33V</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qhc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qhc OCA], [https://pdbe.org/4qhc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qhc RCSB], [https://www.ebi.ac.uk/pdbsum/4qhc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qhc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BLAC_MYCTU BLAC_MYCTU] 

==See Also==
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Blanchard J]]
[[Category: Hazra S]]