View source for 4qhu


==Crystal Structure of IL-17A/Fab6785 complex==
<StructureSection load='4qhu' size='340' side='right'caption='[[4qhu]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4qhu]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QHU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QHU FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qhu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qhu OCA], [https://pdbe.org/4qhu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qhu RCSB], [https://www.ebi.ac.uk/pdbsum/4qhu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qhu ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/IL17_HUMAN IL17_HUMAN] Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts.

==See Also==
*[[Interleukin 3D structures|Interleukin 3D structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Gilliland GL]]
[[Category: Luo J]]
[[Category: Malia T]]
[[Category: Obmolova G]]
[[Category: Teplyakov A]]