View source for 4qmi


==The XMAP215 family drives microtubule polymerization using a structurally diverse TOG array==
<StructureSection load='4qmi' size='340' side='right'caption='[[4qmi]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4qmi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QMI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QMI FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qmi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qmi OCA], [https://pdbe.org/4qmi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qmi RCSB], [https://www.ebi.ac.uk/pdbsum/4qmi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qmi ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CKAP5_HUMAN CKAP5_HUMAN] Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles.<ref>PMID:12569123</ref> <ref>PMID:21646404</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Currie JD]]
[[Category: Fox JC]]
[[Category: Howard AE]]
[[Category: Rogers SL]]
[[Category: Slep KC]]