View source for 4qnc


==Crystal structure of a SemiSWEET in an occluded state==
<StructureSection load='4qnc' size='340' side='right'caption='[[4qnc]], [[Resolution|resolution]] 2.39&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4qnc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Leptospira_biflexa_serovar_Patoc_strain_'Patoc_1_(Paris)' Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QNC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QNC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.388&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MYS:PENTADECANE'>MYS</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qnc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qnc OCA], [https://pdbe.org/4qnc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qnc RCSB], [https://www.ebi.ac.uk/pdbsum/4qnc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qnc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SWEET_LEPBP SWEET_LEPBP] The homodimer mediates transmembrane sugar transport down a concentration gradient. Transport is probably effected by rocking-type movements, where a cargo-binding cavity opens first on one and then on the other side of the membrane.<ref>PMID:25186729</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Liang F]]
[[Category: Perry K]]
[[Category: Yan X]]
[[Category: Yuyong T]]