View source for 4qnn


==Crystal Structure of phospholipase A 1 from hornet(Vespa basalis) venom==
<StructureSection load='4qnn' size='340' side='right'caption='[[4qnn]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4qnn]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Vespa_basalis Vespa basalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QNN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QNN FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qnn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qnn OCA], [https://pdbe.org/4qnn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qnn RCSB], [https://www.ebi.ac.uk/pdbsum/4qnn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qnn ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PA1_VESBA PA1_VESBA] Catalyzes the hydrolysis of phosphatidylcholine with phospholipase A1 activity (By similarity). Shows potent hemolytic activity that is responsible for its lethal effect (PubMed:26603193). May act as an allergen (By similarity). In vivo, induces local inflammatory effects (PubMed:7687388).[UniProtKB:P0DMB4]<ref>PMID:7687388</ref> <ref>PMID:26603193</ref> 

==See Also==
*[[Phospholipase A1|Phospholipase A1]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Vespa basalis]]
[[Category: Chuang CY]]
[[Category: Hou MH]]
[[Category: Ko TP]]
[[Category: Wang AHJ]]