View source for 4qro


==CRYSTAL STRUCTURE of DIHYDROXYBENZOIC ACID DECARBBOXYLASE BPRO_2061 (TARGET EFI-500288) FROM POLAROMONAS SP. JS666 WITH BOUND MANGANESE AND AN INHIBITOR, 2-NITRORESORCINOL==
<StructureSection load='4qro' size='340' side='right'caption='[[4qro]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4qro]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Polaromonas_sp._JS666 Polaromonas sp. JS666]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QRO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QRO FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=38L:2-NITROBENZENE-1,3-DIOL'>38L</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BCT:BICARBONATE+ION'>BCT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qro FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qro OCA], [https://pdbe.org/4qro PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qro RCSB], [https://www.ebi.ac.uk/pdbsum/4qro PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qro ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GRDC_POLSJ GRDC_POLSJ] Involved in the gamma-resorcylate (2,6-dihydroxybenzoate) catabolism (Probable). Catalyzes the reversible decarboxylation of gamma-resorcylate to resorcinol (PubMed:29283551). Also catalyzes the decarboxylation of 2,3-dihydroxybenzoate to catechol, 2,4,6-trihydroxybenzoate to benzene-1,3,5-triol, and 2,6-dihydroxy-4-methylbenzoate to 5-methylbenzene-1,3-diol (PubMed:29283551).<ref>PMID:29283551</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Polaromonas sp. JS666]]
[[Category: Almo SC]]
[[Category: Bhosle R]]
[[Category: Gerlt JA]]
[[Category: Patskovsky Y]]
[[Category: Raushel M]]
[[Category: Toro R]]
[[Category: Vladimirova A]]