View source for 4qur


==Crystal Structure of stachydrine demethylase in complex with cyanide, oxygen, and N-methyl proline in a new orientation==
<StructureSection load='4qur' size='340' side='right'caption='[[4qur]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4qur]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sinorhizobium_meliloti_1021 Sinorhizobium meliloti 1021]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QUR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QUR FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.759&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3BY:1-METHYL-L-PROLINE'>3BY</scene>, <scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qur FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qur OCA], [https://pdbe.org/4qur PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qur RCSB], [https://www.ebi.ac.uk/pdbsum/4qur PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qur ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/STC2_RHIME STC2_RHIME] Monooxygenase involved in the catabolism of stachydrine (L-proline betaine), a source of carbon and nitrogen (PubMed:10689197, PubMed:22224443). Part of a Rieske-type oxygenase system that catalyzes the demethylation of stachydrine to produce N-methyl-L-proline (monomethylproline) (PubMed:22224443). Stc2 is the catalytic subunit (PubMed:22224443).<ref>PMID:10689197</ref> <ref>PMID:22224443</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Sinorhizobium meliloti 1021]]
[[Category: Agarwal R]]
[[Category: Almo SC]]
[[Category: Andi B]]
[[Category: Bonanno JB]]
[[Category: Gizzi A]]
[[Category: Orville AM]]