View source for 4r71


==Structure of the Qbeta holoenzyme complex in the P1211 crystal form==
<StructureSection load='4r71' size='340' side='right'caption='[[4r71]], [[Resolution|resolution]] 3.21&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4r71]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Escherichia_virus_Qbeta Escherichia virus Qbeta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R71 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4R71 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.21&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4r71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r71 OCA], [https://pdbe.org/4r71 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4r71 RCSB], [https://www.ebi.ac.uk/pdbsum/4r71 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4r71 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/EFTU2_ECOLI EFTU2_ECOLI] This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.[HAMAP-Rule:MF_00118]  May play an important regulatory role in cell growth and in the bacterial response to nutrient deprivation.[HAMAP-Rule:MF_00118][https://www.uniprot.org/uniprot/EFTS_ECOLI EFTS_ECOLI] Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.[HAMAP-Rule:MF_00050]

==See Also==
*[[Elongation factor 3D structures|Elongation factor 3D structures]]
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
*[[Ribosomal protein S1|Ribosomal protein S1]]
__TOC__
</StructureSection>
[[Category: Escherichia coli K-12]]
[[Category: Escherichia virus Qbeta]]
[[Category: Large Structures]]
[[Category: Brodersen DE]]
[[Category: Chetverin AB]]
[[Category: Gytz H]]
[[Category: Knudsen CR]]
[[Category: Kutlubaeva Z]]
[[Category: Seweryn P]]