View source for 4rbn


==The crystal structure of Nitrosomonas europaea sucrose synthase: Insights into the evolutionary origin of sucrose metabolism in prokaryotes==
<StructureSection load='4rbn' size='340' side='right'caption='[[4rbn]], [[Resolution|resolution]] 3.05&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4rbn]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Nitrosomonas_europaea Nitrosomonas europaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RBN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RBN FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.05&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rbn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rbn OCA], [https://pdbe.org/4rbn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rbn RCSB], [https://www.ebi.ac.uk/pdbsum/4rbn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rbn ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SUS_NITEU SUS_NITEU] Catalyzes the reversible conversion of sucrose and a nucleotide disphosphate (NDP) into fructose and NDP-glucose; although the reaction is freely reversible in vitro, the physiological reaction seems to be sucrose cleavage. Unlike characterized plant enzymes prefers ADP as a cosubstrate, whereas plants prefer UDP (PubMed:25846332, PubMed:26013491). The KM for sucrose is 8-fold lower in the presence of ADP than UDP (PubMed:25846332). Its preference for ADP over UDP suggests it may directly link sucrose and glycogen metabolism (Probable).<ref>PMID:25846332</ref> <ref>PMID:26013491</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Nitrosomonas europaea]]
[[Category: Asencion Diez MD]]
[[Category: Ballicora MA]]
[[Category: Figueroa CM]]
[[Category: Iglesias AA]]
[[Category: Liu D]]
[[Category: Machtey M]]
[[Category: Wu R]]