View source for 4rgj


==Apo crystal structure of CDPK4 from Plasmodium falciparum, PF3D7_0717500==
<StructureSection load='4rgj' size='340' side='right'caption='[[4rgj]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4rgj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RGJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RGJ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.303&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rgj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rgj OCA], [https://pdbe.org/4rgj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rgj RCSB], [https://www.ebi.ac.uk/pdbsum/4rgj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rgj ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CDPK4_PLAF7 CDPK4_PLAF7] Calcium-dependent kinase that plays a central role in the sexual reproduction and mosquito transmission of P.falciparum. Required for cell cycle progression in the male gametocyte, an essential step in parasite transmission to the mosquito (By similarity).

==See Also==
*[[Calcium-dependent protein kinase|Calcium-dependent protein kinase]]
*[[Calcium/calmodulin dependent protein kinase 3D structures|Calcium/calmodulin dependent protein kinase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Plasmodium falciparum]]
[[Category: Amani M]]
[[Category: Arrowsmith CH]]
[[Category: Bountra C]]
[[Category: Edwards AM]]
[[Category: He H]]
[[Category: Hui R]]
[[Category: Hutchinson A]]
[[Category: Lin YH]]
[[Category: Loppnau P]]
[[Category: Lovato DV]]
[[Category: Neculai M]]
[[Category: Ravichandran M]]
[[Category: Seitova A]]
[[Category: Walker JR]]
[[Category: Wernimont AK]]