View source for 4rjx


==Crystal structure of the OprO mutant protein F62Y/D114Y==
<StructureSection load='4rjx' size='340' side='right'caption='[[4rjx]], [[Resolution|resolution]] 1.54&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4rjx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RJX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RJX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.54&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rjx OCA], [https://pdbe.org/4rjx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rjx RCSB], [https://www.ebi.ac.uk/pdbsum/4rjx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rjx ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PORO_PSEAE PORO_PSEAE] Anion specific, the binding site has higher affinity for phosphate than chloride ions. Porin O has a higher affinity for polyphosphates (tripolyphosphate and pyrophosphate) while porin P has a higher affinity for orthophosphate.

==See Also==
*[[Porin 3D structures|Porin 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pseudomonas aeruginosa PAO1]]
[[Category: Van den Berg B]]