View source for 4ro1


==An 3'-5'-exoribonuclease that specifically recognizes RNAs.==
<StructureSection load='4ro1' size='340' side='right'caption='[[4ro1]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4ro1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RO1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RO1 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.803&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ro1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ro1 OCA], [https://pdbe.org/4ro1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ro1 RCSB], [https://www.ebi.ac.uk/pdbsum/4ro1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ro1 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DI3L2_SCHPO DI3L2_SCHPO] 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'.[HAMAP-Rule:MF_03045]<ref>PMID:23503588</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Schizosaccharomyces pombe 972h-]]
[[Category: Lv H]]
[[Category: Teng M]]
[[Category: Zhu Y]]