View source for 4rqg


==Crystal structure of Rhodostomin==
<StructureSection load='4rqg' size='340' side='right'caption='[[4rqg]], [[Resolution|resolution]] 1.66&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4rqg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Calloselasma_rhodostoma Calloselasma rhodostoma]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RQG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RQG FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.66&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rqg OCA], [https://pdbe.org/4rqg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rqg RCSB], [https://www.ebi.ac.uk/pdbsum/4rqg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rqg ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/VM2RH_CALRH VM2RH_CALRH] Metalloproteinase rhodostoxin: snake venom metalloproteinase that impairs hemostasis in the envenomed animal (By similarity).  Disintegrin rhodostomin: inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3).

==See Also==
*[[Disintegrin|Disintegrin]]
__TOC__
</StructureSection>
[[Category: Calloselasma rhodostoma]]
[[Category: Large Structures]]
[[Category: Chang YT]]
[[Category: Chuang WJ]]
[[Category: Huang CH]]
[[Category: Jeng WY]]
[[Category: Shiu JH]]