View source for 4rsi


==Yeast Smc2-Smc4 hinge domain with extended coiled coils==
<StructureSection load='4rsi' size='340' side='right'caption='[[4rsi]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4rsi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RSI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RSI FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rsi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rsi OCA], [https://pdbe.org/4rsi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rsi RCSB], [https://www.ebi.ac.uk/pdbsum/4rsi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rsi ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SMC2_YEAST SMC2_YEAST] Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
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</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Oh BH]]
[[Category: Shin HC]]
[[Category: Soh YM]]