View source for 4rvi


==Crystal structure of multidrug-resistant clinical isolate A02 HIV-1 protease in complex with non-peptidic inhibitor, GRL0519==
<StructureSection load='4rvi' size='340' side='right'caption='[[4rvi]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4rvi]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RVI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RVI FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.99&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=G52:(3R,3AS,3BR,6AS,7AS)-OCTAHYDRODIFURO[2,3-B 3,2-D]FURAN-3-YL+[(1S,2R)-1-BENZYL-2-HYDROXY-3-{[(4-METHOXYPHENYL)SULFONYL](2-METHYLPROPYL)AMINO}PROPYL]CARBAMATE'>G52</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rvi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rvi OCA], [https://pdbe.org/4rvi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rvi RCSB], [https://www.ebi.ac.uk/pdbsum/4rvi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rvi ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q9J006_9HIV1 Q9J006_9HIV1] 

==See Also==
*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]]
__TOC__
</StructureSection>
[[Category: Human immunodeficiency virus 1]]
[[Category: Large Structures]]
[[Category: Das D]]
[[Category: Garimella H]]
[[Category: Ghosh AK]]
[[Category: Kaufman JD]]
[[Category: Mitsuya H]]
[[Category: Wingfield PT]]
[[Category: Yedidi RS]]