View source for 4s12


==1.55 Angstrom Crystal Structure of N-acetylmuramic acid 6-phosphate Etherase from Yersinia enterocolitica.==
<StructureSection load='4s12' size='340' side='right'caption='[[4s12]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4s12]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_enterocolitica_subsp._palearctica_Y11 Yersinia enterocolitica subsp. palearctica Y11]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4S12 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4S12 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4s12 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4s12 OCA], [https://pdbe.org/4s12 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4s12 RCSB], [https://www.ebi.ac.uk/pdbsum/4s12 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4s12 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A0H2UKZ5_YERE1 A0A0H2UKZ5_YERE1] Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.[HAMAP-Rule:MF_00068]
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</StructureSection>
[[Category: Large Structures]]
[[Category: Yersinia enterocolitica subsp. palearctica Y11]]
[[Category: Anderson WF]]
[[Category: Dubrovska I]]
[[Category: Flores K]]
[[Category: Grimshaw S]]
[[Category: Kwon K]]
[[Category: Minasov G]]
[[Category: Shuvalova L]]