View source for 4s2q


==Crystal Structure of HMG domain of the chondrogenesis master regulator, Sox9 in complex with ChIP-Seq identified DNA element==
<StructureSection load='4s2q' size='340' side='right'caption='[[4s2q]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4s2q]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4S2Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4S2Q FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4s2q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4s2q OCA], [https://pdbe.org/4s2q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4s2q RCSB], [https://www.ebi.ac.uk/pdbsum/4s2q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4s2q ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SOX9_MOUSE SOX9_MOUSE] Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes (By similarity).
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Synthetic construct]]
[[Category: Kolatkar PR]]
[[Category: Lescar J]]
[[Category: Moovarkumudalvan B]]
[[Category: Vivekanandan S]]