View source for 4uvi


==Discovery of pyrimidine isoxazoles InhA in complex with compound 23==
<StructureSection load='4uvi' size='340' side='right'caption='[[4uvi]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4uvi]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UVI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UVI FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.73&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KXU:5-{[(4,6-DIMETHYLPYRIMIDIN-2-YL)SULFANYL]METHYL}-N-[(2-METHYLPYRIDIN-4-YL)METHYL]-1,2-OXAZOLE-3-CARBOXAMIDE'>KXU</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uvi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uvi OCA], [https://pdbe.org/4uvi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uvi RCSB], [https://www.ebi.ac.uk/pdbsum/4uvi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uvi ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/INHA_MYCTU INHA_MYCTU] 

==See Also==
*[[Enoyl-Acyl-Carrier Protein Reductase 3D structures|Enoyl-Acyl-Carrier Protein Reductase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Cowan S]]
[[Category: Ghorpade S]]
[[Category: Gingell H]]
[[Category: Madhavapeddi P]]
[[Category: Read JA]]