View source for 4wxl


==Crystal structure of a peptide deformylase from Haemophilus influenzae complex with Actinonin==
<StructureSection load='4wxl' size='340' side='right'caption='[[4wxl]], [[Resolution|resolution]] 2.33&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4wxl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae_86-028NP Haemophilus influenzae 86-028NP]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WXL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WXL FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.33&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BB2:ACTINONIN'>BB2</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wxl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wxl OCA], [https://pdbe.org/4wxl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wxl RCSB], [https://www.ebi.ac.uk/pdbsum/4wxl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wxl ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DEF_HAEI8 DEF_HAEI8] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
__TOC__
</StructureSection>
[[Category: Haemophilus influenzae 86-028NP]]
[[Category: Large Structures]]
[[Category: Addlagatta A]]
[[Category: Kishor C]]