View source for 4x39


==Gallus interleukin-1 beta mutant - T117A==
<StructureSection load='4x39' size='340' side='right'caption='[[4x39]], [[Resolution|resolution]] 1.61&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4x39]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X39 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4X39 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.61&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4x39 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x39 OCA], [https://pdbe.org/4x39 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4x39 RCSB], [https://www.ebi.ac.uk/pdbsum/4x39 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4x39 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/O73909_CHICK O73909_CHICK] Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity).[RuleBase:RU003753]

==See Also==
*[[Interleukin 3D structures|Interleukin 3D structures]]
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</StructureSection>
[[Category: Gallus gallus]]
[[Category: Large Structures]]
[[Category: Cheng WT]]
[[Category: Yin HS]]