View source for 4xdv


==Crystal Structure of the L74F/M78V/I80V/L114F mutant of LEH complexed with cyclohexanediol==
<StructureSection load='4xdv' size='340' side='right'caption='[[4xdv]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4xdv]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XDV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XDV FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=40O:(1R,2R)-CYCLOHEXANE-1,2-DIOL'>40O</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xdv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xdv OCA], [https://pdbe.org/4xdv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xdv RCSB], [https://www.ebi.ac.uk/pdbsum/4xdv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xdv ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LIMA_RHOER LIMA_RHOER] Catalyzes the conversion of limonene-1,2-epoxide to limonene-1,2-diol. Can use both the (-) and (+) isomers of limonene-1,2-epoxide as substrates and also has some activity with 1-methylcyclohexene oxide, cyclohexene oxide and indene oxide as substrates.

==See Also==
*[[Epoxide hydrolase 3D structures|Epoxide hydrolase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Rhodococcus erythropolis]]
[[Category: Kong XD]]
[[Category: Lonsdale R]]
[[Category: Reetz MT]]
[[Category: Sun Z]]
[[Category: Xu JH]]
[[Category: Zhou J]]