View source for 4y63


==AAGlyB in complex with amino-acid analogues==
<StructureSection load='4y63' size='340' side='right'caption='[[4y63]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4y63]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y63 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Y63 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=48O:5-DEOXY-5-{[(2S)-2-(TRIAZA-1,2-DIEN-2-IUM-1-YL)PROPANOYL]AMINO}URIDINE'>48O</scene>, <scene name='pdbligand=BHE:OCTYL+2-O-(6-DEOXY-ALPHA-L-GALACTOPYRANOSYL)-BETA-D-GALACTOPYRANOSIDE'>BHE</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4y63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y63 OCA], [https://pdbe.org/4y63 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4y63 RCSB], [https://www.ebi.ac.uk/pdbsum/4y63 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4y63 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BGAT_HUMAN BGAT_HUMAN] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.

==See Also==
*[[Glycosyltransferase 3D structures|Glycosyltransferase 3D structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Cuesta-Seijo JA]]
[[Category: Lafont D]]
[[Category: Palcic MM]]
[[Category: Striebeck A]]
[[Category: Vidal S]]
[[Category: Wang S]]