View source for 4yh5


==Lipomyces starkeyi levoglucosan kinase bound to ADP and Manganese==
<StructureSection load='4yh5' size='340' side='right'caption='[[4yh5]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4yh5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lipomyces_starkeyi Lipomyces starkeyi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YH5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YH5 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4yh5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yh5 OCA], [https://pdbe.org/4yh5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4yh5 RCSB], [https://www.ebi.ac.uk/pdbsum/4yh5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4yh5 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LGK_LIPST LGK_LIPST] Levoglucosan kinase that catalyzes the transfer of a phosphate group from ATP to levoglucosan (1,6-anhydro-beta-D-glucopyranose, LG) to yield glucose 6-phosphate in the presence of magnesium ion and ATP (Ref.1, PubMed:21719279, PubMed:26354439). In addition to the canonical kinase phosphotransfer reaction, the conversion requires cleavage of the 1,6-anhydro ring to allow ATP-dependent phosphorylation of the sugar O-6 atom (Ref.1, PubMed:21719279, PubMed:26354439).<ref>PMID:21719279</ref> <ref>PMID:26354439</ref> <ref>PMID:21719279</ref> 
== References ==
<references/>
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</StructureSection>
[[Category: Large Structures]]
[[Category: Lipomyces starkeyi]]
[[Category: Bacik JP]]