View source for 4yq8


==Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds==
<StructureSection load='4yq8' size='340' side='right'caption='[[4yq8]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4yq8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae_Rd_KW20 Haemophilus influenzae Rd KW20]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YQ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YQ8 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.94&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4FV:4-AMINO-N-[(1R,3S)-3-HYDROXYCYCLOPENTYL]-1,2,5-OXADIAZOLE-3-CARBOXAMIDE'>4FV</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4yq8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yq8 OCA], [https://pdbe.org/4yq8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4yq8 RCSB], [https://www.ebi.ac.uk/pdbsum/4yq8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4yq8 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TRMD_HAEIN TRMD_HAEIN] Specifically methylates guanosine-37 in various tRNAs (By similarity).[HAMAP-Rule:MF_00605]

==See Also==
*[[TRNA methyltransferase 3D structures|TRNA methyltransferase 3D structures]]
__TOC__
</StructureSection>
[[Category: Haemophilus influenzae Rd KW20]]
[[Category: Large Structures]]
[[Category: Bonnette WG]]
[[Category: Elkins PA]]
[[Category: Madauss KP]]
[[Category: Stuckey JA]]