View source for 4yto


==Structure of coiled-coil domain of SYCP1==
<StructureSection load='4yto' size='340' side='right'caption='[[4yto]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4yto]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YTO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YTO FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4yto FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yto OCA], [https://pdbe.org/4yto PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4yto RCSB], [https://www.ebi.ac.uk/pdbsum/4yto PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4yto ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SYCP1_HUMAN SYCP1_HUMAN] Major component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for normal assembly of the central element of the synaptonemal complexes. Required for normal centromere pairing during meiosis. Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility.[UniProtKB:Q62209]
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Park HH]]