View source for 4zlh


==Structure of the LapB cytoplasmic domain at 2 angstroms==
<StructureSection load='4zlh' size='340' side='right'caption='[[4zlh]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4zlh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_O157:H7 Escherichia coli O157:H7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZLH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZLH FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zlh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zlh OCA], [https://pdbe.org/4zlh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zlh RCSB], [https://www.ebi.ac.uk/pdbsum/4zlh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zlh ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LAPB_ECO57 LAPB_ECO57] Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.[HAMAP-Rule:MF_00994]
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</StructureSection>
[[Category: Escherichia coli O157:H7]]
[[Category: Large Structures]]
[[Category: Jia Z]]
[[Category: Prince CC]]