View source for 4zqa


==Crystal Structure of the Sds3 Dimerization Domain==
<StructureSection load='4zqa' size='340' side='right'caption='[[4zqa]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4zqa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZQA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZQA FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zqa OCA], [https://pdbe.org/4zqa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zqa RCSB], [https://www.ebi.ac.uk/pdbsum/4zqa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zqa ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SDS3_MOUSE SDS3_MOUSE] Regulatory protein which represses transcription and augments histone deacetylase activity of HDAC1. May have a potential role in tumor suppressor pathways through regulation of apoptosis. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes (By similarity).
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</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Chan CW]]
[[Category: Clark M]]
[[Category: Mondragon A]]
[[Category: Radhakrishnan I]]