View source for 5ard


==Cooperative bio-metallic selectivity in a tailored protease enables creation of a C-C cross-coupling Heckase==
<StructureSection load='5ard' size='340' side='right'caption='[[5ard]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5ard]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lederbergia_lenta Lederbergia lenta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ARD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ARD FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EI3:5-METHYL-2-(5-METHYLPYRIDIN-2-YL)PYRIDINE'>EI3</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ard FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ard OCA], [https://pdbe.org/5ard PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ard RCSB], [https://www.ebi.ac.uk/pdbsum/5ard PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ard ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SUBS_LEDLE SUBS_LEDLE] Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides.

==See Also==
*[[Subtilisin 3D structures|Subtilisin 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Lederbergia lenta]]
[[Category: Davies GJ]]
[[Category: Davis BG]]
[[Category: Diaz-Rodriguez A]]
[[Category: Mcdonough M]]
[[Category: Offen WA]]
[[Category: Palm-Espling ME]]
[[Category: Pordea A]]
[[Category: Sharma M]]
[[Category: Wormald MR]]