View source for 5bzg


==Crystal structure of the murine CD44 hyaluronan binding domain complex with a small molecule==
<StructureSection load='5bzg' size='340' side='right'caption='[[5bzg]], [[Resolution|resolution]] 2.19&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5bzg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BZG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BZG FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4X6:2-METHYL-1,2,3,4-TETRAHYDROISOQUINOLIN-5-AMINE'>4X6</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bzg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bzg OCA], [https://pdbe.org/5bzg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bzg RCSB], [https://www.ebi.ac.uk/pdbsum/5bzg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bzg ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CD44_MOUSE CD44_MOUSE] Main cell surface receptor for hyaluronate. Adhesion to mucosal high endothelial venule and to types I and VI collagen. Probably involved in matrix adhesion, lymphocyte activation and lymph node homing.

==See Also==
*[[CD44|CD44]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Finzel BC]]
[[Category: Liu LK]]