View source for 5bzp


==Crystal structure of the murine cd44 hyaluronan binding domain complex with a small molecule==
<StructureSection load='5bzp' size='340' side='right'caption='[[5bzp]], [[Resolution|resolution]] 1.23&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5bzp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BZP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BZP FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.23&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4XG:2-[3-(DIMETHYLAMINO)PROPYL]-1,2,3,4-TETRAHYDROISOQUINOLIN-8-AMINE'>4XG</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bzp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bzp OCA], [https://pdbe.org/5bzp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bzp RCSB], [https://www.ebi.ac.uk/pdbsum/5bzp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bzp ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CD44_MOUSE CD44_MOUSE] Main cell surface receptor for hyaluronate. Adhesion to mucosal high endothelial venule and to types I and VI collagen. Probably involved in matrix adhesion, lymphocyte activation and lymph node homing.

==See Also==
*[[CD44|CD44]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Finzel BC]]
[[Category: Liu LK]]