View source for 5bzt


==Crystal structure of the murine cd44 hyaluronan binding domain complex with a small molecule==
<StructureSection load='5bzt' size='340' side='right'caption='[[5bzt]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5bzt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BZT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BZT FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4XJ:2-(1,3-DIMETHOXYPROPAN-2-YL)-1,2,3,4-TETRAHYDROISOQUINOLIN-8-AMINE'>4XJ</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bzt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bzt OCA], [https://pdbe.org/5bzt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bzt RCSB], [https://www.ebi.ac.uk/pdbsum/5bzt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bzt ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CD44_MOUSE CD44_MOUSE] Main cell surface receptor for hyaluronate. Adhesion to mucosal high endothelial venule and to types I and VI collagen. Probably involved in matrix adhesion, lymphocyte activation and lymph node homing.

==See Also==
*[[CD44|CD44]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Finzel BC]]
[[Category: Liu LK]]