View source for 5cpc


==Crystal structure of SopD, a type III secreted virulence effector from Salmonella enterica==
<StructureSection load='5cpc' size='340' side='right'caption='[[5cpc]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5cpc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CPC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CPC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5cpc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cpc OCA], [https://pdbe.org/5cpc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5cpc RCSB], [https://www.ebi.ac.uk/pdbsum/5cpc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5cpc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SOPD_SALTY SOPD_SALTY] Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Contributes to replication in macrophages. Plays a role, cooperatively with SopB, in membrane fission and macropinosome formation during invasion.<ref>PMID:15554961</ref> <ref>PMID:17696999</ref> 
== References ==
<references/>
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</StructureSection>
[[Category: Large Structures]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
[[Category: Cygler M]]
[[Category: Shi R]]