View source for 5cxy


==Structure of a Glycosyltransferase in Complex with Inhibitor==
<StructureSection load='5cxy' size='340' side='right'caption='[[5cxy]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5cxy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CXY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CXY FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=55T:5-O-[(R)-[(S)-[3-(ACETYLAMINO)PHENYL](PHOSPHONO)METHOXY](HYDROXY)PHOSPHORYL]CYTIDINE'>55T</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5cxy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cxy OCA], [https://pdbe.org/5cxy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5cxy RCSB], [https://www.ebi.ac.uk/pdbsum/5cxy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5cxy ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SIA8C_HUMAN SIA8C_HUMAN] May transfer sialic acid through alpha-2,8-linkages to alpha-2,3-linked and alpha-2,8-linked sialic acid of N-linked oligosaccharides of glycoproteins and glycolipids. It can form polysialic acid in vitro directly on alpha-2,3-, alpha-2,6-, or alpha-2,8-linked sialic acid.<ref>PMID:10766765</ref> <ref>PMID:9826427</ref> 

==See Also==
*[[Sialyltransferase 3D structures|Sialyltransferase 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Strynadka NCJ]]
[[Category: Volkers G]]