View source for 5cyw


==Crystal Structure of Vaccinia Virus C7==
<StructureSection load='5cyw' size='340' side='right'caption='[[5cyw]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5cyw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vaccinia_virus_Ankara Vaccinia virus Ankara]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CYW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CYW FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5cyw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cyw OCA], [https://pdbe.org/5cyw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5cyw RCSB], [https://www.ebi.ac.uk/pdbsum/5cyw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5cyw ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/C7_VACCA C7_VACCA] Inhibits antiviral activity induced by type I interferons. Does not block signal transdution of IFN, but is important to counteract the host antiviral state induced by a pre-treatment with IFN (By similarity).
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</StructureSection>
[[Category: Large Structures]]
[[Category: Vaccinia virus Ankara]]
[[Category: Deng J]]
[[Category: Krumm BE]]
[[Category: Li Y]]
[[Category: Meng X]]
[[Category: Xiang Y]]