View source for 5dmq


==Crystal structure of mouse eRF1 in complex with Reverse Transcriptase (RT) of Moloney Murine Leukemia Virus==
<StructureSection load='5dmq' size='340' side='right'caption='[[5dmq]], [[Resolution|resolution]] 4.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5dmq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Moloney_murine_leukemia_virus_isolate_Shinnick Moloney murine leukemia virus isolate Shinnick] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DMQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DMQ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dmq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dmq OCA], [https://pdbe.org/5dmq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dmq RCSB], [https://www.ebi.ac.uk/pdbsum/5dmq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dmq ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ERF1_MOUSE ERF1_MOUSE] Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.
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</StructureSection>
[[Category: Large Structures]]
[[Category: Moloney murine leukemia virus isolate Shinnick]]
[[Category: Mus musculus]]
[[Category: Song H]]
[[Category: Tang T]]