View source for 5dxx


==Crystal structure of Dbr2==
<StructureSection load='5dxx' size='340' side='right'caption='[[5dxx]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5dxx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Artemisia_annua Artemisia annua]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DXX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DXX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dxx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dxx OCA], [https://pdbe.org/5dxx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dxx RCSB], [https://www.ebi.ac.uk/pdbsum/5dxx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dxx ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DBR2_ARTAN DBR2_ARTAN] Involved in the biosynthesis of the antimalarial endoperoxide artemisinin by catalyzing the double bond reduction of (11R)-dihydroartemisinic aldehyde to produce artemisinic aldehyde. Also able to reduce artemisinic alcohol and artemisinic acid to a lesser extent.<ref>PMID:18495659</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Artemisia annua]]
[[Category: Large Structures]]
[[Category: Chen TT]]
[[Category: Li L]]
[[Category: Xu YC]]