View source for 5ewu


==Crystal structure of the Arabidopsis thaliana C-terminal Chlh at 1.25A==
<StructureSection load='5ewu' size='340' side='right'caption='[[5ewu]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5ewu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EWU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EWU FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEZ:BENZOIC+ACID'>BEZ</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ewu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ewu OCA], [https://pdbe.org/5ewu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ewu RCSB], [https://www.ebi.ac.uk/pdbsum/5ewu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ewu ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CHLH_ARATH CHLH_ARATH] Multifunctional protein involved in chlorophyll synthesis, plastid-to-nucleus retrograde signaling and abscisic acid (ABA) perception. In chlorophyll synthesis, catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. The reaction takes place in two steps, with an ATP-dependent activation followed by an ATP-dependent chelation step. In addition to its function in the Mg-chelatase enzyme, is required for the plastid-to-nucleus retrograde signaling. The plastid-to-nucleus signal plays an important role in the coordinated expression of both nuclear- and chloroplast-localized genes that encode photosynthesis-related proteins. Has a role in mediating ABA signaling in stomatal guard cells and during seed germination. Binds ABA and is a positive regulator of ABA signaling.<ref>PMID:11172074</ref> <ref>PMID:17051210</ref> <ref>PMID:19363094</ref> <ref>PMID:19535472</ref> <ref>PMID:20543028</ref> <ref>PMID:21562844</ref> <ref>PMID:23011401</ref> 
== References ==
<references/>
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</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Chen Z]]
[[Category: Jiang L]]
[[Category: Liu Y]]
[[Category: Zhang X]]