View source for 5gsm


==Glycoside hydrolase B with product==
<StructureSection load='5gsm' size='340' side='right'caption='[[5gsm]], [[Resolution|resolution]] 1.27&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5gsm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermococcus_kodakarensis_KOD1 Thermococcus kodakarensis KOD1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GSM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5GSM FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.27&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B3P:2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>B3P</scene>, <scene name='pdbligand=GCS:D-GLUCOSAMINE'>GCS</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PPI:PROPANOIC+ACID'>PPI</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5gsm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gsm OCA], [https://pdbe.org/5gsm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5gsm RCSB], [https://www.ebi.ac.uk/pdbsum/5gsm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5gsm ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GLMA_THEKO GLMA_THEKO] Exo-type enzyme that specifically cleaves the non-reducing terminal glycosidic bond of chitooligosaccharides (PubMed:12923090, PubMed:15136574, PubMed:28130448). Catalyzes the hydrolysis of GlcN-GlcNAc to glucosamine (GlcN) and N-acetylglucosamine (GlcNAc) (PubMed:15136574, PubMed:28130448). Involved in chitin degradation (PubMed:12923090, PubMed:15136574). Can also hydrolyze reduced chitobiose (GlcN2OH) and chitooligosaccharides of various chain lengths (PubMed:12923090).<ref>PMID:12923090</ref> <ref>PMID:15136574</ref> <ref>PMID:28130448</ref> 
== References ==
<references/>
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</StructureSection>
[[Category: Large Structures]]
[[Category: Thermococcus kodakarensis KOD1]]
[[Category: Kamachi S]]
[[Category: Mine S]]
[[Category: Watanabe M]]