View source for 5gxe


==Crystal structure of Acryloyl-CoA reductase AcuI in complex with NADPH==
<StructureSection load='5gxe' size='340' side='right'caption='[[5gxe]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5gxe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ruegeria_pomeroyi_DSS-3 Ruegeria pomeroyi DSS-3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GXE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5GXE FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.696&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5gxe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gxe OCA], [https://pdbe.org/5gxe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5gxe RCSB], [https://www.ebi.ac.uk/pdbsum/5gxe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5gxe ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ACUI_RUEPO ACUI_RUEPO] Probably catalyzes the NADPH-dependent reduction of acrylyl-CoA to propanoyl-CoA. Restores acrylate resistance when expressed in an E.coli strain K12 acuI deletion.<ref>PMID:22563425</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Ruegeria pomeroyi DSS-3]]
[[Category: Cao HY]]
[[Category: Wang P]]
[[Category: Zhang YZ]]